Your guide to Notre Dame football vs Purdue | Odds, predictions and key storylines

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SOUTH BEND — Third-ranked Notre Dame wraps up its mini-tour of the Big Ten Conference this week with a trip to Purdue.

The last time the Irish (3-0) visited West Lafayette in 2024, they washed away the shame of a home loss to Northern Illinois with a 66-7 blasting of the Boilermakers (1-2). Notre Dame opened this season with wins over Wisconsin (Shamrock Series), Rice and Michigan State.

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Kickoff at Ross-Ade Stadium is at 2 p.m. Saturday Sept. 26.

We'll update this story throughout the week with the latest injury news, coach comments, line movement and plenty more. Whether you're looking for kickoff information, key matchups or score predictions, this guide has everything you need to know before the Irish take the field against the Boilermakers.

Notre Dame football injury updates after defeating Michigan State

Aside from safety Luke Talich, who headed to the locker room near the end of a 27-10 win over the Spartans but returned with a sprint for the Alma Mater, the Irish had a quiet night on the health front in Week 3.

Kickoff details for Notre Dame at Purdue

Time: 2:00 p.m. ET

Date: Saturday, Sept. 26

Location: Ross-Ade Stadium (West Lafayette, IN)

How to tune into Notre Dame vs. Purdue: TV, streaming, local radio affiliates

TV: None

Streaming: Peacock

Local radio affiliates: WSBT (960 AM, 96.1 FM), WNSN (101.5 FM)

Tony Simeone is the radio play-by-play voice with Mike Golic Sr. as the analyst.

Latest spread/odds for Notre Dame vs. Purdue

Odds from BetMGM

Point spread: Notre Dame -27

Over/under: 57.5

Moneyline: Purdue +1750, Notre Dame -3000

Our score prediction for Notre Dame football vs. Purdue

This will be updated later in the week.

Mike Berardino covers Notre Dame football for the South Bend Tribune and NDInsider.com. Follow him on social media @MikeBerardino.

This article originally appeared on South Bend Tribune: Your guide to Notre Dame football vs Purdue | Odds, predictions and key storylines

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